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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRN
All Species:
38.18
Human Site:
Y832
Identified Species:
76.36
UniProt:
Q16849
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16849
NP_002837.1
979
105848
Y832
P
D
E
G
A
S
L
Y
H
V
Y
E
V
N
L
Chimpanzee
Pan troglodytes
XP_516107
1019
110215
Y832
P
D
E
G
A
S
L
Y
H
V
Y
E
V
N
L
Rhesus Macaque
Macaca mulatta
XP_001083323
498
55666
E366
V
S
E
H
I
W
C
E
D
F
L
V
R
S
F
Dog
Lupus familis
XP_536080
1066
115628
Y929
P
D
E
G
S
S
L
Y
H
V
Y
E
V
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60673
979
106069
Y832
P
D
E
G
S
S
L
Y
H
V
Y
E
V
N
L
Rat
Rattus norvegicus
Q63259
983
106209
Y836
P
D
E
G
S
S
L
Y
H
V
Y
E
V
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511936
1140
127143
Y993
P
D
E
G
S
N
L
Y
H
I
Y
E
V
N
L
Chicken
Gallus gallus
XP_418552
1017
113861
Y870
P
D
E
G
S
N
L
Y
H
I
Y
E
V
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
Y1763
P
A
E
R
S
A
R
Y
Q
Y
F
V
V
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722672
1306
145632
Y1070
P
E
E
G
A
E
V
Y
H
I
Y
E
V
H
L
Honey Bee
Apis mellifera
XP_623773
902
104556
Y739
P
E
E
G
S
E
L
Y
H
I
Y
E
V
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789889
533
59466
E401
V
S
E
H
V
W
C
E
D
Y
L
V
R
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
34.6
82.8
N.A.
86.9
87.2
N.A.
40.5
41.4
N.A.
20.3
N.A.
29.1
33.4
N.A.
33.4
Protein Similarity:
100
93.2
42
85.6
N.A.
90.8
91.1
N.A.
54.2
55.8
N.A.
31
N.A.
42.2
47.4
N.A.
44
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
80
80
N.A.
26.6
N.A.
66.6
66.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
N.A.
53.3
N.A.
93.3
93.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
25
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
0
0
0
0
0
17
0
0
0
0
9
0
% D
% Glu:
0
17
100
0
0
17
0
17
0
0
0
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
17
% F
% Gly:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
17
0
0
0
0
75
0
0
0
0
17
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
34
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
67
0
0
0
17
0
0
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
0
0
0
59
0
% N
% Pro:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
9
0
0
0
0
0
17
0
0
% R
% Ser:
0
17
0
0
59
42
0
0
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
9
0
9
0
0
42
0
25
84
0
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
17
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _